Barbara Bottazzi Selected Research

PTX3 protein

9/2021	Correction: Siltuximab downregulates interleukin-8 and pentraxin 3 to improve ventilatory status and survival in severe COVID-19.
5/2021	Circulating pentraxin 3 in severe COVID-19 or other pulmonary sepsis.
1/2021	Siltuximab downregulates interleukin-8 and pentraxin 3 to improve ventilatory status and survival in severe COVID-19.
1/2021	The Long Pentraxin PTX3 as a New Biomarker and Pharmacological Target in Age-Related Macular Degeneration and Diabetic Retinopathy.
4/2020	Determination of pentraxin 3 levels in cerebrospinal fluid during central nervous system infections.
3/2020	Imbalance between angiogenic and anti-angiogenic factors in sera from patients with large-vessel vasculitis.
11/2019	Pentraxin 3 deficiency protects from the metabolic inflammation associated to diet-induced obesity.
1/2019	Interaction of C1q With Pentraxin 3 and IgM Revisited: Mutational Studies With Recombinant C1q Variants.
1/2019	Pentraxin 3 in Cardiovascular Disease.
1/2017	Anti-rheumatic treatment is not associated with reduction of pentraxin 3 in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis.

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Barbara Bottazzi Research Topics

Disease

41	Inflammation (Inflammations) 10/2021 - 02/2003
10	Infections 01/2021 - 03/2008
8	Neoplasms (Cancer) 05/2022 - 12/2006
7	COVID-19 01/2022 - 01/2021
7	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 05/2002
4	Sepsis (Septicemia) 11/2021 - 01/2017
4	Rheumatoid Arthritis 01/2021 - 09/2013
3	Fibrosis (Cirrhosis) 01/2021 - 09/2013
3	Rheumatic Diseases (Rheumatism) 01/2017 - 03/2010
3	Coronary Artery Disease (Coronary Atherosclerosis) 01/2017 - 03/2010
2	Septic Shock (Toxic Shock Syndrome) 11/2021 - 01/2017
2	Macular Degeneration (Age-Related Maculopathy) 01/2021 - 01/2020
2	Wounds and Injuries (Trauma) 01/2021 - 01/2016
2	Giant Cell Arteritis (Horton Disease) 03/2020 - 01/2016
2	Takayasu Arteritis (Arteritis, Takayasu's) 03/2020 - 11/2014
2	Essential Thrombocythemia 01/2017 - 02/2011
2	Thrombosis (Thrombus) 01/2017 - 02/2011
2	Polycythemia Vera 01/2017 - 02/2011
2	Communicable Diseases (Infectious Diseases) 01/2017 - 01/2009
2	Pneumonia (Pneumonitis) 10/2014 - 01/2014
2	Acute-Phase Reaction 01/2012 - 04/2010
2	Myocardial Infarction 01/2012 - 07/2011
2	Human Influenza (Influenza) 10/2010 - 03/2008
2	Fibrosarcoma 12/2006 - 03/2006
1	Pancreatic Neoplasms (Pancreatic Cancer) 05/2022
1	Coinfection 11/2021
1	Brain Injuries (Brain Injury) 10/2021
1	Traumatic Brain Injuries (Traumatic Brain Injury) 10/2021
1	Craniocerebral Trauma (Head Injury) 10/2021
1	Persistent Vegetative State (Vegetative State) 10/2021
1	Critical Illness (Critically Ill) 10/2021
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2021
1	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2021
1	Invasive Pulmonary Aspergillosis 01/2021
1	Bacterial Infections (Bacterial Infection) 01/2021
1	Idiopathic Pulmonary Fibrosis 01/2021
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021
1	Central Nervous System Infections (Central Nervous System Infection) 04/2020
1	Vasculitis (Vasculitides) 03/2020
1	Cardiotoxicity 01/2020
1	Blindness (Hysterical Blindness) 01/2020
1	Heart Diseases (Heart Disease) 01/2020
1	Proteinuria 01/2020
1	Yellow Fever 12/2019

Drug/Important Bio-Agent (IBA)

25	PTX3 proteinIBA 09/2021 - 02/2003
17	Biomarkers (Surrogate Marker)IBA 05/2022 - 03/2010
16	Complement System Proteins (Complement)IBA 01/2021 - 01/2010
10	Proteins (Proteins, Gene)FDA Link 05/2022 - 05/2002
10	Pattern Recognition ReceptorsIBA 01/2021 - 07/2004
9	C-Reactive ProteinIBA 01/2017 - 05/2002
5	CytokinesIBA 10/2021 - 12/2006
5	Acute-Phase Proteins (Acute-Phase Protein)IBA 04/2020 - 02/2003
4	Antiviral Agents (Antivirals)IBA 12/2019 - 03/2008
3	AntibodiesIBA 01/2019 - 04/2010
2	AlbuminsIBA 11/2021 - 01/2017
2	Immunoglobulin G (IgG)IBA 11/2021 - 01/2020
2	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2021 - 12/2016
2	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 10/2021 - 09/2005
2	siltuximabIBA 09/2021 - 01/2021
2	Interleukin-8 (Interleukin 8)IBA 09/2021 - 01/2021
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 03/2020 - 07/2004
2	VaccinesIBA 12/2019 - 01/2017
2	Amyloid (Amyloid Fibrils)IBA 01/2016 - 01/2009
2	Interleukin-1 (Interleukin 1)IBA 01/2013 - 06/2003
2	NF-kappa B (NF-kB)IBA 12/2006 - 03/2006
1	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 01/2022
1	Intravenous Immunoglobulins (IVIG)FDA Link 11/2021
1	Immunoglobulin M (IgM)IBA 11/2021
1	Immunoglobulin A (IgA)IBA 11/2021
1	Stem Cell FactorIBA 10/2021
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 10/2021
1	Calcium-Binding ProteinsIBA 10/2021
1	Glial Fibrillary Acidic ProteinIBA 10/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Hemostatics (Antihemorrhagics)IBA 01/2021
1	Serum Amyloid P-ComponentIBA 01/2021
1	FibrinIBA 01/2021
1	PlasminogenIBA 01/2021
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2021
1	Indicators and Reagents (Reagents)IBA 01/2021
1	Antirheumatic Agents (DMARD)IBA 01/2021
1	Biological ProductsIBA 11/2020
1	Protein Isoforms (Isoforms)IBA 11/2020
1	Interleukin-15 (Interleukin 15)IBA 11/2020
1	Angiopoietin-1IBA 03/2020
1	AngiostatinsIBA 03/2020
1	EndostatinsIBA 03/2020
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2020
1	trans-crotonin (CTN)IBA 01/2020
1	BuffersIBA 01/2020
1	Enalapril FDA LinkGeneric 01/2020
1	Phosphates (Orthophosphate)IBA 01/2020
1	TroponinIBA 01/2020
1	AnthracyclinesIBA 01/2020

Therapy/Procedure

4	Therapeutics 01/2019 - 09/2013
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2017 - 09/2013
2	Resuscitation 01/2017 - 10/2015
1	Critical Care (Surgical Intensive Care) 10/2021
1	Hematopoietic Stem Cell Transplantation 01/2021
1	Drug Therapy (Chemotherapy) 01/2020